QUESTION: 32 YO F W/ CC OF DRY, BURNING LIPS Patient is homozygous for MTHFR 677. Has been worked up by myself and multiple other practitioners, including neurology, and nothing abnormal in serum except positive IgG for HHV6 and Mycoplasma. The only thing that has ever helped her is SAMe. She’s experienced a significant but …
QUESTION: I just listened to your antidepressant tapering webcall, and you talked about looking at the patient’s reaction to meds to get a better idea of where their brain needs the most support. I’m wondering about someone put on Lexipro for situational grief, it never helped, she was left on it for 5 years, now …
QUESTION: I have a pt CBS+ and suox + and wanted some baseline measurements and a means to monitor progress. I got a recommendation to use sulfite urine strips, but I couldn’t seem to find them. Is it acceptable to monitor urine sulfate instead? ANSWER: Sulfite is the actual Marker. Sulfate sucks as it is …
URINE SULFITE TESTING FOR SNP MANAGEMENT, A CONVERSATION CONT Read More »
QUESTION: I have an insomnia patient who has both methylation and COMT defects, and I can’t seem to get them to sleep better. When I added in 5-MTHF supplementation, their sleep got worse! They are currently on Ambien, and want to get off, but in the light of their genetics, what do I do? ANSWER: …
SLEEP MEDICATIONS SNPs INSOMNIA AND THERAPY IDEAS CONT Read More »
QUESTION: I have a patient with C677T homozygous, symptoms started after a dose (literally one dose) of Cipro (previously tolerated) in 2008. Can tolerate methyl cobalamin but methyl folate brings on intolerable burning in arms and legs, which stops when she stops the MTHF. She had this symptom originally (along with tendon tears and other …
QUESTION: Why would a pt have asthma exacerbations after taking 1/5 of a methyl guard plus? Compound Heterozygous MTHFR – (she puts in applesauce one pill and eats only 1 spoonful). Her allergy Sx’s are better, though. Will also feel “sped up” and have a panic attack w/increased HR after taking. She’s also incredibly nauseated …
QUESTION: I am following up on our discussion about your treatment protocol for patients that have severe methylation issues, and your slow titrations/nutritional protocols. I discussed with you a patient with COMT homozygous, MTHFR heterozygous, and GST allele absent, who has numerous multi-system complaints and has a pacemaker. He tried only 2 grams of MSM …
THERAPY FOR METHYLATION SNPS, GLUCURONIDATION AND SULFATION REACTION SUPPORT CONT Read More »
QUESTION: Do you happen to have an MS protocol? I need to slow down the progression. ANSWER: Depends a bit on duration on length of disease. If less than 5 years I generally look at methylation, vitamin D, curcumin, and glutathione. I also consider heavy metals, infections etc. Also add some PTC (oral or IV) …
MULTIPLE SCLEROSIS TREATMENT CONSIDERATIONS CONT Read More »
QUESTION: I have a 16 year old patient who had mono 6 years ago, she has never recovered. She has waves of violent illness that may involve joints, muscles, gastric pain and diarrhea, severe sore throat, cough and most severe a sudden drop of her platelets. It is not uncommon for her to miss 40 …
QUESTION 1: I have several patients right now who seem to suffer from histamine and mast cell disorders. Do you start with one supplement at a time. If you do, how long do you have to wait to start the additional supplement. From my understanding the process is to start with methyl B12-> methyl folate-> …
A CONVERSATION ON HISTAMINE REACTIONS AND SUPPLEMENT DOSING CONT Read More »
QUESTION: A: A 35 yo female patient of mine is having really weird reactions to foods. She is on an SCD/low histamine diet and avoiding IgG food reactions. Still, 1-2x/week she is experiencing what she refers to as “throat closing” or throat tightness within 10-15mins of eating. The food triggers are random and inconsistent. The …
Most have seen this: Warning: Improving your methylation may trigger an EBV relapse This article points to the idea of “correcting methylation causes EBV relapse”. In one sense, true BUT: without working genomics and especially methylation one becomes (much more likely to be) a chronic re-activator of EBV and other HHV Viri. We saw this association …
QUESTION: As you are the SNP/Methylation man – I’m wondering if you have any resources on GSTT1 deletion and how to support a healthy 30y/o female looking for preventative care. I understand that this gene is responsible for binding environmental toxins to glutathione so that it can be neutralized. I’m not sure that giving support, …
MY QUESTIONS ARE: What is a way to attempt to think globally about autoimmunity so I can consider as many potential causes when beginning a diagnostic and therapeutic approach? ANSWERS: Autoimmune cause areas to consider – Multiple cause areas can be considered and identified – Generally in most autoimmunity there are multisystem considerations Follow therapy, …
Methylation – Part 1” 2-12-15 What is methylation, how does it relate to the MTHFR defect and how does this affect health?
