Glutathione Archives - Consult Dr. Anderson

Separating Intravenous Ascorbic Acid [IV Ascorbate] and Glutathione on the same Day in Oxidative Therapies. Rationale and limitations of clinical timing.

Dr. Paul S. Anderson While non-oxidant doses of intravenous vitamin c (IVC) and glutathione (GSH) are synergistic in support of the ReDox cascade between physiological compartments (Cytosol-Cell Membrane-Plasma-Plasma Lipids)* it was previously theorized that an oxidant therapy such as high dose IVC (HDIVC) may be defeated by addition of GSH in proximity. Chen et. al …

Separating Intravenous Ascorbic Acid [IV Ascorbate] and Glutathione on the same Day in Oxidative Therapies. Rationale and limitations of clinical timing. Read More »

Myelodysplasia: Potential Therapies

Dr. Paul S. Anderson Based on known data regarding MDS and its etiology as well as potential therapies (see below) there is a low probability of ‘cure’ using known therapies. Supportive care is the mainstay of therapy especially in patients over 60 years of age. Oxidative treatments are indicated, as well as transplantation, growth factors, …

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VITAMIN A and ACCUTANE TOXICITY NOTES

Dr. PAUL S. ANDERSON METABOLISM – ELIMINATION: Vitamin A: Cytochrome p450, and especially CYP3A4 oxidizing excess retinol, Vitamin D intake (a known CYP3A4-inducer), iron intake (CYP3A4 has an iron center), Copper and vitamin C. Accutane (13-cisRA) cytochrome P450 enzymes (CYPs) including 2C8, 3A7, 4A11, 1B1, 2B6 and 2C9 responsible for the generation of 13-cisRA …

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Fluoroquinolone (FQ) Toxicity Potential Therapy

Paul S. Anderson For some time in pharmacology courses and review classes I have mentioned the potential for tendinopathy and other related and unrelated pathologies following the use of the fluoroquinolone drug class. The seemingly obvious mechanism is probably too simplistic, but appears to be supported by the recent review paper quoted below: “The exact …

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Sulfur Dioxide VOG Considerations

Sulfur dioxide is water soluble and an immediate stress on the respiratory apparatus, and then the cardiovascular and neurological systems to name a few. It is primary detoxified via SUOX which can be slow for three reasons: SUOX SNPs, heavy metal effect such as tungsten and cofactor insufficiency (molybdenum). Of note this detox pathway is …

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IV Glutathione in epileptic patients

Is it safe to administer IV glutathione in an epileptic patient on keppra and with cerebral palsy? And… Have you administered IV glutathione in patients with g6pd deficiency given the redox cycle in red blood cells? Dr. Anderson: Clinically I have seen no problem with epileptics, Keppra and GSH, same with G6PD deficiency (actually is …

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Glutathione and epilepsy medication

Clinical Case Questions: IVs Administered: Is it safe to administer IV glutathione in a patient with cerebral palsy, on epileptic medication – with no seizures for the last 5 years? She has pretty severe psoriasis as well…hoping that something like glutathione IV is beneficial. Thanks for your teaching and help! Dr. Anderson: Generally very safe. …

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TRAUMATIC BRAIN INJURY AND INTEGRATIVE MEDICINE IN PRACTICE

BLOG AND LITERATURE REVIEW REFERENCE: Understanding the neuroinflammatory response following concussion to develop treatment strategies. Neuroinflammation is becoming more and more associated in the literature with a host of downstream comorbidities including depression, anxiety, addictive behavior, dementia and others. Concussion and the traumatic brain injury that follows can be devastating to the health and long …

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PEDIATRIC AML IV IDEAS CONT

QUESTION: The case is more tricky just because of the little girl’s age. At 9 months of age she was diagnosed with AML subtype M7. Chemo was started right away and at the time my role was to support chemotherapy with homeopathy and treat the mother with supplementation as she is actively nursing. She made …

PEDIATRIC AML IV IDEAS CONT Read More »

SODIUM THIOSULFATE, ASCORBATE AND OTHER THIOLS CONT

QUESTION: I am working with an oncologist who is worried about me using glutathione and HDIVC in a shared cancer patient who is also getting sodium thiosulfate, to lessen the side effects (neuropathy) of cisplatin, because he says it is his understanding that there is significant concern about timing and use of anything that can …

SODIUM THIOSULFATE, ASCORBATE AND OTHER THIOLS CONT Read More »

SHEEHAN’S OR SIMMOND’S TREATMENT PROTOCOL CONT

QUESTION: Have you treated Sheehan’s syndrome? If so, what have you found effective? ANSWER: 1: In any case treat “what you see” and correct any gross deficit hormonally 2: Treating sooner = easier course in every case I have seen 3: Early cases can resolve with less therapy and I have seen HTH and PIT …

SHEEHAN’S OR SIMMOND’S TREATMENT PROTOCOL CONT Read More »

POST STROKE THERAPY CONT

QUESTION: 51 year old female patient, with malignant hypertensive heart disease (yrs of being un medicated, she is an athlete, free diver etc), ischemic stroke 2 months ago, some hemiplegia and hemiparesis, post-stroke meds: carvedilol, lisinopril, simvastatin, losartan, aspirin. Very healthy otherwise, BP managed well now. Are there any contraindications to IV therapy with glutathione …

POST STROKE THERAPY CONT Read More »

MTHFR IN INFANTS CONT

QUESTION: Do you have experience in treating gene defect in infants? 7 month old homozygous for either A677T or A1298CC (mother couldn’t remember, but the child was tested). Normal growth and development, but after last vaccine (dtap) she got tremors 25 hours later that resolved over 2 weeks. Mother has homozygous MTHFR defect that created …

MTHFR IN INFANTS CONT Read More »

THERAPY FOR METHYLATION SNPS, GLUCURONIDATION AND SULFATION REACTION SUPPORT CONT

QUESTION: I am following up on our discussion about your treatment protocol for patients that have severe methylation issues, and your slow titrations/nutritional protocols. I discussed with you a patient with COMT homozygous, MTHFR heterozygous, and GST allele absent, who has numerous multi-system complaints and has a pacemaker. He tried only 2 grams of MSM …

THERAPY FOR METHYLATION SNPS, GLUCURONIDATION AND SULFATION REACTION SUPPORT CONT Read More »

ATYPICAL REACTIONS TO MAGNESIUM CONT

QUESTION: I gave a patient IV magnesium, and they had symptoms that were opposite to what I would imagine magnesium would do; muscle cramps etc. Why did this happen? Are there tests I can run to avoid this happening in other patients in the future? ANSWER: If you look at the “adverse events” of IV …

ATYPICAL REACTIONS TO MAGNESIUM CONT Read More »

END STAGE LIVER DISEASE TREATMENT IDEAS CONT

QUESTION: I have a 71 y.o male patient with Liver failure and d/t his age he is not a candidate for liver transplant… The Liver problem started with Wilson’s dz–> NASH–> now ascites and platelet and CBC dropping low–> they drain ascites weekly and blood transfusion happens every other week now–> Prognosis is 6-12 months …

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IV VITAMIN C POST TREATMENT SIDE EFFECTS CONT

QUESTION: I have a patient who feels terrible after receiving HDIVC therapy. If is such a great therapy, why is this person reacting badly? ANSWER: While not common, these reactions do happen and if they do not abate with dose reduction etc are a reason to discontinue IVC. The potential theoretical reasons we have surmised …

IV VITAMIN C POST TREATMENT SIDE EFFECTS CONT Read More »

VITAMIN C FOR GLUTATHIONE SUPPORT CONT

QUESTION: In reviewing Radiation Recovery info from files and several IV seminars I still need clarification on the glutathione. My understanding was no glutathione on the same day as HDIVC. The Augmented Glutathione (Radiation Recovery) Formula from 1/2014 has a GSH preload. There is 25 grams of Vit C in the formula. Can you help …

VITAMIN C FOR GLUTATHIONE SUPPORT CONT Read More »

IV GLUTATHIONE IN CANCER THERAPY CONT

QUESTION: I had a quick question about glutathione. I read that its half-life is relatively short (a couple days), and one of our cancer patients is asking about getting it in between IV vitamin C treatments. Do you typically do the IV glutathione twice a week because of the short half-life? Also, on average, how …

IV GLUTATHIONE IN CANCER THERAPY CONT Read More »

MULTIPLE SCLEROSIS TREATMENT CONSIDERATIONS CONT

QUESTION: Do you happen to have an MS protocol? I need to slow down the progression. ANSWER: Depends a bit on duration on length of disease. If less than 5 years I generally look at methylation, vitamin D, curcumin, and glutathione. I also consider heavy metals, infections etc. Also add some PTC (oral or IV) …

MULTIPLE SCLEROSIS TREATMENT CONSIDERATIONS CONT Read More »

IV THERAPY POST MI CONT

QUESTION: I have a patient with prostate cancer and a rising PSA after prostatectomy. He’s coming off a lupron shot, which is when the PSA started increasing. I treated him with basic naturopathic care with attention to the cancer, including 50 g AA twice weekly for a month. He has now had a massive heart …

IV THERAPY POST MI CONT Read More »

IV GLUTATHIONE ADMINISTRATION CONT

QUESTION: Can I just put glutathione in a Vit-Min IV bag with the rest of the nutrients? ANSWER: The point with infusing glutathione (GSH) is to preserve the reduced glutathione (GSH) you paid the pharmacy to make until it gets into the patients body. If you mix it in many nutrient IV bags it will …

IV GLUTATHIONE ADMINISTRATION CONT Read More »

IV THERAPY AND RADIATION TREATMENTS CONT

QUESTION: What is the best way to use IV therapy to augment radiation treatments? ANSWERS: We use the following schedule of therapy in the post-Radiation patient: 2X a week for 4-8 weeks depending on level of Rad side effects 1X a week for 8 weeks 1X every 2 weeks until Sx stabilized or resolved Oral …

IV THERAPY AND RADIATION TREATMENTS CONT Read More »

HISTAMINE REACTIONS AND SNPS CONT

QUESTION: A: A 35 yo female patient of mine is having really weird reactions to foods. She is on an SCD/low histamine diet and avoiding IgG food reactions. Still, 1-2x/week she is experiencing what she refers to as “throat closing” or throat tightness within 10-15mins of eating. The food triggers are random and inconsistent. The …

HISTAMINE REACTIONS AND SNPS CONT Read More »

HIGH INTRACELLULAR MAGNESIUM – A CONVERSATION CONT

QUESTION: I have an out of state patient with fibromyalgia who has had high magnesium levels on RBC testing. She was previously taking alkacalm for chronic muscle pain but stopped taking it after the initial test showed high Mg. However, 3 months later, it is still the same. Is this a common finding in fibromyalgia? …

HIGH INTRACELLULAR MAGNESIUM – A CONVERSATION CONT Read More »

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