ASC

6B – Leukemia and Oxidative Therapies Including Intravenous Ascorbic Acid / HDIVC

[gdlr_button href=”https://www.consultdranderson.com/wp-content/uploads/securepdfs/2019/10/6B-2019-IVC-Ascorbate-Leukemia-Update.pdf” target=”_blank” size=”large” background=”#ed4b2f” color=”#ffffff”]Download PDF[/gdlr_button] A seeming conundrum regarding the ability of some leukemic cells (i.e. CLL) to sequester ascorbate (ASC) has led to confusion regarding the safety and utility of high dose ascorbate delivered via IV (HDIVC).  This has led to some apparent confusion between this concern and the apparent positive benefits …

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REDOX BIOLOGY

Design: Four systematic review papers published in the past two years all take a different approach to describe our ever evolving and deepening understanding of the activity of Reductive-Oxidative balance (ReDox). These four papers (and many like them) have sought to update the scientific community in regard to our ever evolving understanding of this precariously …

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GLUTATHIONE OPTIMIZATION CONT

QUESTION: Why is there sometimes a diminished return with glutathione, and the benefits seem to plateau? ANSWER: This document is about what we did to help the GSH work in a radiation injury model of neurodegeneration. What we were finding is that with a lot of the neuro cases the GSH dose had to go …

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IV VITAMIN C AND GSH INTERACTIONS WITH SODIUM THIOSULFATE USED FOR OTOPROTECTION Cont

QUESTION: Below is an oncologist’s receptive response to my patient’s mom (pt is a 4 y/o NED in maintenance therapy after dx with meduloblastoma) requesting to do IV Vitamin C and possibly glutathione after cisplatin. I am not familiar with any interaction with the drug in question sodium thiosulfate (STS) (giving it for otoprotection as …

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