QUESTION: I have a patient who no longer seems to be reacting to standard IV ABX and naturopathic treatments for Lyme.
ANSWER: Thoughts of where to start:
1. Mitochondria get really injured through Tx. They need a lot of support for a long time to come online – worse with mito SNP’s but bad anyway. All the usual characters for support and some membrane stabilizers are required. 2. Endocrine support often is touchy but adrenal and thyroid can be moving targets at this stage and require tweaking often. Thyroid resistance can be persistent and T3 Rx is often required in tandem with aggressive cortisol management. See Webcall for more information.
3. Neurosteroid imbalance is universal and leads to the agitation and neuroinflammation. Increasing a dose of progesterone in oil or a Troche (HS) is almost universally needed and sometimes Pregnenolone as well. Along with this, use NAC to reduce glutamate activity and lower brain inflammation.
4. Biofilms block progress at this point, so treat them as well
5. Other infections are often active even when labs are equivocal. HHV series is common. I’d consider acyclovir as a trial for 4 weeks.
6. At this point I’d do a “push-pull” IV protocol: 1 immune IV, I rotate H2O2 and ART-HDIVC once a week with a nutrient + GSH + PolyMVA on another day of the week. A 4-6 week trial is required. More can obviously be done, but often some of this works at this stage.