I have a patient with nodular regenerative hyperplasia secondary to high dose chemotherapy. He is a 31 year old white male s/p autologous stem cell transplant in March 2016, for recurrence of hodgekin’s lymphoma. The chemotherapies in which the patient has received include, busulfan, mephalan, zyracidonic acid, gemzar, nivolumab, brentuximab. Patient has elevated, alkphos, AST and ALT with slight elevation in bilirubin. There is no hepatospelenomegaly, but patient did have enlarged spleen which was likely related to lymphoma and or ITP which patient responded to IVIG. The main clinical question is, What protocol would be best for this patient?
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