First, although they say this is “very rare”, in the populations we often treat it is not. Second, I spoke with an immunologist and asked how likely a false positive with an IgM is, and he said it’s such a large and unique molecule a true false positive IgM is exceedingly rare. (“Especially if symptomatic” …
Persistent IgM and Acute-phase Antibodies – EBV and other Infections Read More »
EBV Diagnosis CE 2.0 Total | 1.0 of which are Pharm This course discussed the appropriate diagnosis and treatment of EBV. It includes lab testing, patient assessment, comorbidity and global treatment with prescription and natural medicines. Got a question? Head to the forum! Every Webinar has an associated, private forum. If you have a question, …
#01 05.15 EBV Diagnosis, Treatment, and Management Read More »
Most have seen this: Warning: Improving your methylation may trigger an EBV relapse This article points to the idea of “correcting methylation causes EBV relapse”. In one sense, true BUT: without working genomics and especially methylation one becomes (much more likely to be) a chronic re-activator of EBV and other HHV Viri. We saw this association …
QUESTION: What is the best drug therapy for EBV reactivation? Can you recommend any supplements for it? ANSWER: In reactivated cases of EBV with symptoms (pending a negative HIV) I learned from the Chief of Infectious Disease at San Fran General to give 800 mg Acyclovir TID with food for 60 days and re-assess. (You …
QUESTION: If a patient is positive for antibodies for EBV VCA IgG, EBV EA IgG, EBV NA IgG and negative for antibodies for EBV VCA IgM, does this indicate the tail-end of a primary infection or a re-activation? CBC and CMP unremarkable. ANSWER: Positive EaIgG indicates an active reinfection (or maybe primary IF IgM is …
Many early human trials of Acyclovir in EBV showed positive effect on viral load reduction but were never run long enough to actually assist the immune system in eradication or marginalizing the virus. Examples such as this one and others prove this point: [Andersson J, Sköldenberg B, Ernberg I, Britton S, Henle W, Andersson U. …
BACKGROUND: “Mycoplasma” refers to any organism within the class Mollicutes, composed of five genera (Mycoplasma, Ureaplasma, Acholeplasma, Anaeroplasma, and Asteroloplasma). Over 120 named “Mycoplasma” species exist with13 Mycoplasma species, two Acholeplasma species, and one Ureaplasma species have been isolated from humans. However, only three species are well-established human pathogens (but others likely exist): Mycoplasma pneumoniae, …
Pt A: 57 y/o female with h/o Sjogren’s, possible intestinal scleroderma/MCTD, chronic pain on 3-4 Tramadol a day and topical CBD oil, chronic low iron/ferritin, fatigue. I just diagnosed her with Lyme on Labcorp WB. 2 +IgM bands. Coinfections we know of: HHV6 6.62, neg EBV/CMV/mycoplasma/c.pneum/parvo etc. Labs: E2 <5 on low dose E2/P patch, …
QUESTION: Patient with History of Fatigue and sleepiness. * Hashimotos Thyroid (mild elevation of both Tg and TPO Ab) * Over weight, under slept , etc * Found ASO titer Elevated (218) * High EBV chronic markers (EBV IgG VAC and NA both > 5.00 (quest max sensitivity)) * High Mycoplasma p. (IgG titer 1.43) …
QUESTION: I was at Doc Talks and saw your talk on Artesunate. I am wanting to try it for a pt I have with chronic fatigue and reactivated EBV. All I have in notes is Artesunate and its use in cancer pts. You mentioned that you had used it for EBV, but I didn’t get the …
QUESTION: I have a pt with Labrix urinary test showing low levels of neurotransmitters across the board (I.e. low serotonin, dopamine, norepinephrine, epinephrine, gaba, glutamate). Has used ecstasy regularly in the past – though not a giant dose and not more than once every 6 weeks according to pt. Also used Provigil off-label for depression for …
WELLBUTRIN, CHRONIC VIRI, NEUROTRANSMITTER TESTING, AND FATIGUE CONT Read More »
QUESTION: We have adopted using your viral panel. Could you explain how you interpret a positive IgG in any of the following: Chlamydia pneumoniae, Mycoplasma pneumoniae, Parvo, HHV 6, EBV. My understanding is that IgM being positive is current infection (and for EBV the early antigen). What if IgG is positive? Do you ever test …
QUESTION: Have you ever treated Hashimotos encephalopathy? ANSWER: Yes sadly I have. The Cliff note version: If ambulatory, ramp doses of oral Boswellia up to 3-4 grams a day, along with 1-2 grams Meriva or BCQ TID. LDN can help as well, and Melatonin 5-10 MG HS. In addition to that I’d hunt for EBV …
QUESTION: I have a 57 YO Menopausal Female who is an avid runner with migrating joint pain. What labs would you run to help diagnose what is wrong with her? ANSWER: Lab Investigation Rationale: First basic labs to make sure no imbalanced electrolytes, elevated LFTs, Anemia etc. Then, inflammatory rheumatologic labs (Sed or CRP / …
MIGRATING JOINT PAIN, TESTING CONSIDERATIONS CONT Read More »
QUESTION: I have two patients (one female 56yo (PI) and one male 50yo (GP)) that have high levels of EBV EA (24 for PI, >150 for GP). So I started them on valtrex 1g bid, did myer’s IV on both, IVC on female and first IVC on male tomorrow. Along with adrenal support, niacel for …
IV VITAMIN C PEARLS FOR CHRONIC VIRI TREATMENT CONT Read More »
QUESTION: I have a 16 year old patient who had mono 6 years ago, she has never recovered. She has waves of violent illness that may involve joints, muscles, gastric pain and diarrhea, severe sore throat, cough and most severe a sudden drop of her platelets. It is not uncommon for her to miss 40 …
QUESTION: Viral testing for CFS/fibromyalgia interpretation HHV6 IgG 1:160 H CMV IgG > 5.00 H EBV EA IgG EBV VCA IgM negative EBV VCA IgG 4.77 H EBV EBNA IgG >5.00 H Are the positive HHV6 and EBV results just indicating past infection (and not significant) but the CMV considered active and requiring tx? Is …
QUESTION: I have a patient and I’d like to draw her for the CMV, EBV, and HHV-6, we’ve tried a bunch of stuff already, but I’d like it to be covered. Thoughts? ANSWER: Generally, I do the following for chronic ID screening. The asterisk (*) ones are if we are limiting to ‘most likely’ positives …